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Graphical Illustration of the Difference Between Genetic Susceptibility and Predisposition
At our recent conference Genomic Analysis in Tort Cases, one of the panels focused primarily on communicating genomic issues to juries and judges, including extensive slides and comments from Magna Legal on communicating the concepts of genetic predisposition and “susceptibility” to cancer, where the defense often seeks to make genetic predisposition arguments and plaintiffs often leverage arguments related to susceptibility. The panel provided examples of graphical illustrations of the differences between genetic susceptibility and predisposition, as well examples for explaining internal (endogenous) sources of germline and somatic mutations, and genomic analyses (or not) as factors for differential etiology.
The slides from this panel can be downloaded by completing the form below. The panel included David Schwartz, PhD (Innovative Science Solutions), Scott M. Horwitz (National Director of Graphic Consulting, Magna Legal Services, Chicago, IL), and Mark G. Zellmer, Esq. (Husch Blackwell, St. Louis, MO).
Graphical Illustration of the Difference Between Genetic Susceptibility and Predisposition