Category Archives: Mesothelioma

ToxicoGenomica

2023 Brings Multiple Waves Of Additional Studies Regarding Mesotheliomas And Other Cancers Caused Solely By Genomic Factors

| September 5, 2023

ToxicoGenomica recently presented a webinar organized by Perrin Conferences and the slides are now available for download. The webinar focused on the latest publications, scientific studies, and statistics regarding genomics role in cancers. It also covered predictive software and other tools for understanding the impact of germline mutations on disease development and progression. The speakers […]

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Key Developments in the Use of Genomics in Mesothelioma Cases: Causal Role of BAP1 Null (Loss of Function) Mutations in Mesothelioma and Key Legal Findings

| December 19, 2022

ToxicoGenomica recently presented a webinar organized by Perrin Conferences and the slides are now available for download. The title of the session was Key Developments: Genomics in Mesothelioma Cases. The webinar focused on the latest cases, the most recent science and publications, and the evolving applications and cost of deployment of the science of genomics […]

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Webinar – Legal and Ethical Challenges in Mesothelioma Cases Involving Young People

| September 1, 2020

For first of its kind new data related to the growing number of lawsuits involving young people with mesothelioma, please join next week’s Perrin webinar: Legal and Ethical Challenges in Young Mesothelioma Cases. One key fact is the cases often involve people who have medical histories that include a range of benign tumors, cysts, cancers and/or […]

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Scientist looking at DNA

New Data Suggest Over-representation of Young Females in 108 Talc-Exposed Mesothelioma Cases Reported by Drs. Moline and Kradin – A Data Compilation

| April 29, 2020

For talc/asbestos litigation, a notable development in 2020 was the publication of two case series articles involving a total of 108 persons who developed mesothelioma.  The authors concluded that all 108 persons could be characterized as having exposure to asbestos only through cosmetic talcum powder. The authors include Dr.  Jacqueline Moline and Dr. Richard Kradin, […]

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Genomic Evidence Essential to Asbestos and Talc Cases: Dr. Len van Zyl Presents at Perrin National Conference

| September 19, 2019

On September 9, Dr. Len van Zyl of ToxicoGenomica presented at Perrin Conferences’ National Asbestos Litigation Conference at the Fairmont San Francisco Hotel. The conference was greatly attended, and attendees were provided with key information on the trends that are currently driving asbestos litigation and the impact these trends may have on future cases. Dr. […]

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Perrin conference

The Application of Genomics in Asbestos and Talc Cases: Dr. Len van Zyl will be Speaking at the Perrin National Asbestos Litigation Conference

| August 14, 2019

On September 9-11, Dr. Len van Zyl of ToxicoGenomica will be speaking at Perrin Conferences’ National Asbestos Litigation Conference at the  Fairmont San Francisco Hotel, San Francisco, CA. This marks the tenth anniversary of the three-day conference which provides attendees with a deeper understanding of the trends currently driving asbestos litigation and the impact these […]

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DNA

Why Do BAP1 Mutations Cause Mesothelioma?

| May 6, 2019

Mechanistic understanding of cancers continues to accelerate, with important implications for tort litigation. A recent new study by He et al. (2019) provides new insights into how and why germline BAP1 mutations are involved in the development of some cancers, such as mesothelioma, but not others. The new insights are about tissue specific actions of […]

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Expert Planning Meeting for National Mesothelioma Patient Registry – March 26, 2019 in Bethesda

| February 19, 2019

At long last, plans are moving forward to establish a national mesothelioma patient registry in the United States. A key meeting of experts planning the registry will be held on Tuesday March 26, 2019  in Bethesda. The meeting will include panel presentations by mesothelioma experts from CDC and NIOSH, and will include a substantial opportunity for […]

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journal of clinical oncology

New Evidence of Genetic Drivers for Mesothelioma In Persons With No Known Asbestos Exposure

| November 12, 2018

A recently published article authored by Drs. Michele Carbone, Haining Yang, and Harvey Pass (among others) is relevant to asbestos and talc defendants because it provides additional data supporting the conclusion that inherited genetic variations cause mesothelioma in some persons without any known exposure to asbestos. Most notably for asbestos and talc litigants, 57 out […]

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Hand is inserting sequence of DNA. Genetic engineering, GMO and Gene manipulation concept.

New Paper Explores Heritable Genetic Factors Related To Mesothelioma

| October 8, 2018

A new paper by Kharazmi and colleagues present important data regarding the heritable nature of mesothelioma using epidemiological techniques to analyze the population-based Swedish Cancer Registry. The results, reported in the European Journal of Cancer, are important because the findings confirm that both genes and exposures are relevant, and on their face, appear helpful to […]

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